Stability constants of zinc complexes affect common cold treatment results

Zinc for the common cold.

BACKGROUND The common cold is one of the most widespread illnesses and is a leading cause of visits to the doctor and absenteeism from school and work. Trials conducted in high-income countries since 1984 investigating the role of zinc for the common cold symptoms have had mixed results. Inadequate treatment masking and reduced bioavailability of zinc from some formulations have been cited as i...

Spectrophotometric Study of Stability Constants of Metal Complexes of Promethazine at Different Temperatures

The complexation reactions between Cu2+, Pd2+ and Ni2+ metal ions with promethazine (PM) in water or DMF were studied by the spectrophotometric methods at [(15, 25,35 and 45±0.1) °C]. The complexation process was optimized in terms of pH, temperature and contact time. The stoichiometry of the complex was found to be 1:1 (metal ion/ligand). The formation constants of the resulting complexes were...

Stability Constants Determination of Mandelate Complexes of Coba1t(II), Nickel(II) and Zinc(II)

Determination of the composition and stability of metal-ion mandelate complexes was performed as a part of systematic investigations of unsubstituted and substituted metal-ion monocarboxylate complexes in our laboratory. The intention was to give some insight into factors governing the stability of these complexes-. In order to complete this study the same experimental conditions (i. e. tempera...

Treatment of the common cold.

The common cold is a viral illness that affects persons of all ages, prompting frequent use of over-the-counter and prescription medications and alternative remedies. Treatment focuses on relieving symptoms (e.g., cough, nasal congestion, rhinorrhea). Dextromethorphan may be beneficial in adults with cough, but its effectiveness has not been demonstrated in children and adolescents. Codeine has...

Critical Evaluation of Equilibrium Constants in Solution Part A: Stability Constants of Metal Complexes CRITICAL SURVEY OF STABILITY CONSTANTS OF NTA COMPLEXES